What is systemic autoimmune disease

What are the different types of systemic disease? How do I reversed my autoimmune disease? What is the most severe autoimmune disease? An autoimmune disease is a condition arising from an abnormal immune response to a normal body part.

There are at least types of autoimmune diseases.

Nearly any body part can be involved. Common symptoms include low grade fever and feeling tired. Often symptoms come and go. The cause is generally unknown.

Some autoimmune diseases such as lupus run in families, and certain cases may be triggered by infections or other environmental factors. Systemic Lupus Erythematosus ( SLE ) is one of the examples of systemic autoimmune diseases in which there is production of wide spectrum of serum autoantibodies. The peak incidence for females is in late middle age, and is somewhat later for males.

In all age groups except neonates, lupus is more common in females than males. Autoimmune diseases can be broadly divided into two types depending on the principal clinical and pathological disease features: those that damage many organs (systemic), and those where only a single organ or tissue is directly damaged by the autoimmune process (localized). Systemic autoimmune diseases are often characterized by autoantibodies reactive with a wide variety of autoantigens including DNA, cell surface molecules, and intracellular matrix proteins. In systemic diseases the immune system attacks self antigens in several organs. Systemic lupus erythematosus, for example, is characterized by inflammation of the skin, joints, and kidneys, among other organs.

See all full list on webmd. The immune system normally guards against germs like bacteria and viruses. When it senses these foreign invaders, it sends out an army of fighter cells to attack them. Systemic autoimmune rheumatic diseases are different from most autoimmune diseases in that they affect many organs, cells or tissues simultaneously rather than just one.

Common autoimmune diseases include type diabetes, rheumatoid arthritis, and inflammatory bowel disease. These are sometimes referred to collagen vascular diseases or connective tissue disorders-but this is wrong. Systemic sclerosis can affect many body parts, from skin and blood vessels to organs, muscles, and joints. Symptoms depend on the type you have.

They can include: Calcium lumps under your skin. Dry mouth, eyes, skin, or vagina.

Heart, kidney, or lung problems. Stiff, swollen, warm, or tender joints. As far as I know, there are no cures for autoimmune diseases like rheumatoid arthritis and lupus. The best that can be done is treat the symptoms. The outcome depends on the disease.

Most autoimmune diseases are chronic, but many can be controlled with treatment. When symptoms get worse, it is called a flare-up.